Welcome to the Grattoni Lab!

Transforming chronic disease outcomes through nanotechnology-based therapeutic innovations

We are in the Department of Nanomedicine of the Houston Methodist Research Institute in Houston, Texas.

Leveraging the latest advancements in nanotechnology, our mission is to modernize medicine through innovations in drug and cell delivery. We develop implantable devices for various therapeutic applications including long-term drug delivery, cell encapsulation, cancer treatment and vaccine platforms. From exploring nanoscale molecular transport to preclinical studies in disease-relevant models, we focus on improving the treatment and prevention of chronic diseases. Occasionally, we take our research to new heights by performing studies aboard the International Space Station.

By integrating our core expertise in engineering, chemistry, medicine and cancer biology, we aim at creating the next-generation of transformational healthcare technologies.

Grattoni’s Lab Research Focus

Long-acting drug delivery

Remotely tunable drug delivery

Cell encapsulation

Intratumoral immunotherapy

Local immunomodulation

Space nanomedicine

Grattoni’s Lab Research Focus

Long-acting drug delivery

Remotely tunable drug delivery

Cell encapsulation

Intratumoral immunotherapy

Local immunomodulation

Space nanomedicine

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Research Support

Our research is supported by the Houston Methodist Research Institute (HMRI), National Institutes of Health (NIH), Department of Defense (DOD), Gilead Sciences, Juvenile Diabetes Research Foundation, among other federal and private funding agencies.

Research Support

Our research is supported by the Houston Methodist Research Institute (HMRI), National Institutes of Health (NIH), Department of Defense (DOD), Gilead Sciences, Juvenile Diabetes Research Foundation, among other federal and private funding agencies.

Logos of funding partners